Melioidosis is an emerging infection in Brazil and neighbouring South American countries.The wide range of clinical presentations include severe community-acquired pneumonia, septicaemia, central nervous system infection and less severe soft tissue infection.Diagnosis depends heavily on the clinical microbiology laboratory for culture.Burkholderia
Abstract Intratumor heterogeneity of tumor clones and an immunosuppressive microenvironment in cancer ecosystems contribute to inherent difficulties for tumor treatment.Recently, chimeric antigen receptor (CAR) T-cell therapy has been successfully applied in the treatment of B-cell malignancies, underscoring its great potential in antitumor therapy
Fish Oils Abstract Innervation of the hypothalamic median eminence by Gonadotropin-Releasing Hormone (GnRH) neurons is vital to ensure puberty onset and successful reproduction.However, the molecular and cellular mechanisms underlying median eminence development and pubertal timing are incompletely understood.Here we show that Semaphorin-6A is stro
Bosnia and Herzegovina is the first country in Europe for unemployment and percentage of inhabitants who do not live in the country where they were born.These data require a very serious approach with a wide range of reasons for these phenomena especially from geographical point of view.Thus, it is necessary to critically investigate its regional s